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The decreased reproductive performance of SLC7A11 knockout male mice was supported by a high proportion of immature spermatozoa in the cauda epididymis, although there were no significant differences in cysteine and GSH levels in the testis compared to controls, suggesting GSH synthesized by xCT is considered to be an important antioxidant [76]

When the collagen levels diminish further, it accentuates the wrinkles on the skin

FIGURE 5 As shown in Figure 5B, the quantitative analysis of reactive oxygen species (ROS) levels showed that the OGD/R group had a significant increase in ROS levels compared to the control group

Reactive oxygen species also affect the activity of transcription factors that control metabolic enzyme expression

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