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Intravenous administration of lipoic acid at doses of 600 mg/day for three weeks (112) and oral lipoic acid at doses as high as 1,800 mg/day for six months (113) and 1,200 mg/day for two years (76) did not result in serious adverse effects when used to treat diabetic peripheral neuropathy
10.1023/A:1015557300450 168 WahibahN
Moreover, most clinical cancer therapies, including conventional chemotherapies 8 , radiotherapy 9 , or recent immune therapies 10,11 , have also been reported to undermine female fertility in various ways, which further distracts researchers attention on NRTP-induced ovarian damage