While its been deemed safe as a topical or oral agent, the chemical seems to cause harm when inhaled
After 48 h, cells were pretreated for 15 min with either no antagonist, TRPA1 antagonist, or TRPM8 antagonist
In Singapore, officials have sounded the alarm over vape products containing the anesthetic etomidate, which a 2024 study described as "an ultrashort-acting non-barbiturate sedative." Similarly, in the U.K., parents and public officials have expressed dismay over the rise of vape products containing synthetic cannabinoids known as "spice," which have been known to cause serious health problems and severe withdrawal symptoms
The tobacco manufacturers have looked at safer and less polluting filters, but none has found widespread market acceptance yet
It was meant to be a temporary fix, but the state quickly saw the benefits of making it a permanent part of New Jerseys tax code