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GLP-1RA/tesaglitazar (50 nmol kg 1 per day) also led to a greater decrease in body weight and food intake relative to DIO mice treated with a fixed dose combination of the GLP-1RA and tesaglitazar (Extended Data Fig

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High solids loading increases agglomeration (the situation in which mall powder particles stick together and form clumps) grittiness poor wetting nonuniform particle distribution risk of dose variability, instability/separation An ointment mill produces much higher and more controlled shear forces than an EMP