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Little House on the Prairie's leading man Michael Landon, who died in 1991, couldn't have been more different to his wholesome, loving, father character on the hit show, according to former co-stars Alison Arngrim, who played Nellie Oleson (right) in the hit 1970s show, described Landon as manic' and claimed he 'drank, smoked' told 'terrible jokes' on set of the NBC series Grassle, 79, who played Little House matriarch Caroline 'Ma' Ingalls, also struggled with alcoholism and admits in her book that her addiction 'completely contributed to the relationship to what it was.' Arngrim said she agreed that Landon was a world away from the wholesome family loving farmer portrayed on the hit show

Circulation 111 , 143149 (2005)

The study, funded by NHLBI, appeared in the American Journal of Physiology-Heart and Circulatory Physiology .

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