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These findings unveil a distinct regulatory axis in which nutrient sensing by astrocytes fine-tunes inflammatory and oxidative responses at the level of protein translation, revealing a novel mechanism by which substrate availability modulates enzyme activity during neuroinflammation 123

Vitamin B 12 deficiency is a common cause of megaloblastic anemia, various neuropsychiatric symptoms, and other clinical manifestations

During intense exercise, your body experiences increased metabolic demands that vitamin B12 helps address through multiple pathways

Enzyme activities were re-evaluated 24 h after start of pre-culture

Death and survival of heterozygous lurcher purkinje cells in vitro