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However, these studies only explored the association of cancer incidence with tobacco consumption and did not examine the role of dysbiosis in oral microbiome due to tobacco consumption in the progression of the disease

[21] According to StraitsResearch, The India pan masala market is expected to reach US$10,365 million by 2026 at the CAGR of 10.4% during the forecast period 20192026

Studies show that at least 3% of American adults get their tobacco fix by using smokeless tobacco, and this number is expected to rise as smoking bans are enforced across the country

Once addiction takes hold, users find themselves compelled to use nicotine to avoid withdrawal symptoms and to maintain the pleasurable effects, creating a reinforcing cycle of dependence