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According to the National Cancer Institute, there are at least 28 chemicals in smokeless tobacco that have been found to cause various forms of cancer, including esophageal cancer, cancers of the mouth and pancreatic cancer

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Michael Siegel, from the Boston University School of Public Health

Tasters described the combined mixture as milder, more coffee-like, and overall, more pleasant, while pure caffeine was harsh, alkaloid, medical bitterness, alkaloid being the sharp, drug-like quality that compounds like caffeine can carry on their own

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