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The opening comes following the announcement from the Public Health England Report which estimates e-cigarettes are 95% less harmful to health than a normal cigarette and the recently introduced regulation for the EC, TPD (Tobacco Product Directive) whereby products have to be compliant with the regulation by May 2017

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A further limitation of the existing literature is that most population-based studies have classified cigarette smoking and e-cigarette use crudely, often treating e-cigarette use as a binary variable without distinguishing between exclusive e-cigarette users, dual users, and former smokers who no longer use any nicotine product

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