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In a 2022 review of 21 placebo-controlled randomized trials that tested a broad swath of purported hangover-prevention ingredients, researchers concluded only very low quality evidence of efficacy is available to recommend any pharmacologically active intervention for the treatment or prevention of alcohol-induced hangover. What causes hangoversand can these products really do anything about it

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However, this method is non-specific because many carbonyl compounds such as some oxidized unsaturated fatty acids have been shown to react with TBA and interfere with MDA measurement (198)

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