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Limited Human Safety Data : Long-term effects, optimal dosing, and potential complications in humans remain unknown

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Unlike traditional single-receptor GLP-1 agonists, Tirzepatide functions as a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist

These side effects are more likely if you have diabetes and are on diabetes medications like insulin or sulfonylureas