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Harm Reduction Approaches For those choosing to use tobacco despite known risks, certain practices may reduce exposure levels: Using less tobacco per cigarette reduces intake per smoke Filtering reduces tar and particulate matter Organic, additive-free tobacco eliminates some chemical exposures Spacing cigarettes further apart decreases daily consumption None of these approaches make tobacco safethey merely adjust exposure levels

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however endogenous ligands that have demonstrated activity at these receptors also have activity for GPR119 [74]

Disclaimer: Adults need around 2000 kcals a day (not applicable to non-food products or pet food)