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Some people have slower-acting versions of CYP2A6, which results in nicotine staying in their system for a longer time, while others have more efficient variants that break down nicotine more quickly

Skull (1887) by Vincent van Gogh

This helps to maintain a consistent level of nicotine in the body, reducing the peaks and troughs associated with smoking cigarettes

She recalled: The thing that blew my mind was when you came in for a cuddle, and I was like, Sorry, you smoke!" Jessie went on to express her astonishment, adding: I didnt think dancers smoked, and you had a power fag before we did the bloody run-through

In a 2019 study, Chen and colleagues (opens in new window) set out to further explore this effect and understand whether this expression pattern also occurs in normal cells in vitro