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Biomarkers The levels of S-WBC, S-CRP, total S-Cholesterol, S-HDL, S-LDL, and S-fibrinogen did not change appreciably over time and no statistically significant differences between the treatment groups were observed (data not shown)

In addition to the internal documents, The Times consulted more than a dozen tobacco researchers, policy experts and historians, and reviewed patent applications and publicly available videos of Juuls founders discussing their product over the course of a decade

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However, e-cigarettes are not an FDA-approved quit aid, and there is no conclusive scientific evidence on the effectiveness of e-cigarettes for long-term smoking cessation