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These observations align well with the concept of Anna Karenina principle for animal microbiomes (Zaneveld et al., 2017), which refer to a more variable microbial community composition in dysbiotic individuals compared to healthy individuals

Nat Rev Nephrol 13(6):368380 Vlachopoulos C, Ioakeimidis N, Abdelrasoul M, Terentes-Printzios D, Georgakopoulos C, Pietri P et al (2016) Electronic cigarette smoking increases aortic stiffness and blood pressure in young smokers

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I never lose sight of the miracle of it

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