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Induction of renal and pancreatic injuries by cyclosporine (15 mg/kg/day) in rats was treated by l-carnitine (50 or 200 mg/kg/day) for a month, the result of which was inhibition of LC3-II and caspase-3 expression, suppression of 8-OHdG and TGF-1 expression, improved inflammation and renal function, decreased HbA1c and plasma glucose levels, and elevated plasma insulin level [80]

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