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N Engl J Med, 2025

PMID 33809596

The key signs associated with the condition are as follows: Numbness or a tingling sensation in the cheek or jaw Sudden, intense bursts of severe pain Frequent occurrences of aches and pains Brief, sharp shocks of pain that can feel like stabbing or electric Unexpected pain episodes triggered by routine activities A persistent burning feeling affecting one side of the face This condition primarily occurs due to the disruption of the normal functioning of the trigeminal nerve

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Smart (2007) and Smart (2014) extended these observations to post-MI cardiac regeneration