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died of a methadone overdose in 2010
However, perhaps even more so than with the evidence base regarding e-cigarettes, the risks posed by Tobacco Heating Products are as yet not well characterised and placing such products on a continuum of risk is again largely a matter of educated conjecture based on toxicant emissions, toxicant exposure, and biological testing data
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Dependence is distinct from addiction, as it involves physical adaptation rather than compulsive misuse
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