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Supporters say the increase could stop 5,700 kids from starting to smoke and prompt nearly 21,000 adults to quit within the first year

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Another study on human organotypic oral epithelial cultures showed that IQOS, compared to CS, yielded less cytotoxicity (significant after 48 h post-exposure), secretion of proinflammatory mediators, and gene expression perturbations related to apoptosis, necroptosis, senescence, xenobiotic metabolism, and oxidative stress 58

Their long-term value and growing interest in personalization further accelerate global adoption

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