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Both pivotal trials demonstrated that ecnoglutide injection provides comprehensive clinical benefits, including effective glycemic control, significant weight reduction, and improvements in key metabolic parameterswith sustained efficacy over 52 weeks and a favorable safety and tolerability profile
10.1007/s00403-010-1045-4
doi: 10.14814/phy2.15620
Both incretin mimetics and DPP-4 inhibitors have a low risk of hypoglycaemia when used alone because they work in a glucose-dependent manner, meaning their effects diminish as blood glucose normalises
Moreover formulation (L-carnitine vs propionyl-/acetyl-L-carnitine), dose, route, timing relative to ischemia/reperfusion, and treatment duration of L carnitine (short peri-procedural courses vs chronic supplementation) may contribute to these differences (Da Silva Guimares et al
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