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Some suggest that e-cigarettes likely confer lower risk compared to combustible tobacco cigarettes, because they do not expose users to toxicants produced through combustion

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The duration and severity of nicotine withdrawal can vary depending on factors such as the level of nicotine dependence, duration of tobacco use, and individual differences in biology and psychology

Artificial dyes like Blue 1 or Yellow 5 may be present, especially in brightly colored varieties