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3.4.2 Effects of glucose metabolic reprogramming on lipid and amino acid metabolism Reprogrammed glucose metabolism primarily impacts two areas

Its levels decrease as a result of aging, stress and exposure to toxins

Eur J Cancer 2005

Yamashita K, Miyazaki T, Fukuda Y, Mitsuyama J, Saijo T, Shimamura S, et al

However, notably in a PCP model of schizophrenia, only 30 mg/kg, but not 3 or 10 mg/kg, rescued defects in hyperlocomotion and PPI, in stark contrast to cell culture models where lower models were more beneficial ( in vivo (Table 2)