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doi: 10.4049/jimmunol.168.1.348 23 Ben-OthmanRFlanneryARMiguelDCWardDMKaplanJAndrewsNW

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Norman Swan : It was a big study, 438,000 by the time they brought everybody together in this review

For driver mutations, samples from individuals exposed to both tobacco and alcohol were characterized by a particularly high TP53 frequency of mutations (87.0% (141/162), 71.4% (25/35), 68.8% (22/32) and 55.6% (20/36) in the tobacco plus alcohol, alcohol alone, tobacco alone and unexposed groups, respectively