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In 3-AR knockout mice, however, no effect was observed with AOD9604 confirming the dependency of its chronic lipolytic action on 3-AR expression, while also suggesting an additional acute mechanism that may operate through a separate pathway

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Monitor the compounds clinical development if it remains of interest

It's studied for mobilizing stored fat (lipolysis) and blocking new fat storage (lipogenesis) through adipose-tissue pathways, without engaging appetite or insulin signaling