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3 The smoke of one light or low-tar cigarette inhaled by a human may contain almost 2 to 3 times the amount of tar and nicotine compared to the smoke from the same cigarette taken in by the smoking machines

It also calls on Congress to pass legislation requiring e-cigarette manufacturers to pay fees to the FDA that would help fund the agencys regulatory activities

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and (c) smoking can induce the metabolism of various therapeutic agents and their pharmacological and/or clinical effects