The level of nicotine in the blood depends on the amount of nicotine in the smokeless tobacco product, the tobacco cut size, the products pH (a measure of its acidity or basicity), and other factors (3)
surgeon general calling e-cigarette use a major public health concern, this may not be the case
As one review stated, "Nicotine is the addictive chemical in tobacco smoke, but its involvement in smoking-related harm (outside pregnancy) is very small, if any, compared to cigarette smoking." Another systematic review pointed out that nicotine can have a variety of potential health effects, from raising one's cardiovascular risk to causing birth defects in pregnant women
Wu P, Wilson K, Dimoulas P, et al
While the long-term health impacts of pouches are still uncertain and side effectslike gum irritation and negative gastrointestinal and cardiovascular symptomshave been reported, she noted, any possible adverse effects pale in comparison to those associated with cigarettes