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1a) includes a signal peptide (SP), glicentin-related polypeptide (GRPP), glucagon (GCG), intermediate peptides-1 and -2 (IP-1 and IP-2), glucagon like peptides 1 and 2 (GLP-1 and GLP-2), and is proteolytically processed into the mature glucagon-like peptides

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The OBS all adjusted for age, sex, and concomitant medications, and the majority adjusted for at least a proxy for disease severity, and as such there can be considered to be limited remaining residual confounding