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The association of the variant GPX4 genotypes with the increased risk of CS in hypertensives remained statistically significant after adjusting for confounding variables such as sex, body mass index (BMI), blood pressure and antihypertensive medication use (OR=2.18, 95%CI 1.463.27, P =0.0015)

Fowler, & M

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Soon after this, in 1788, Thomas Crawley, another English physician, suggested on the basis of one of his clinical cases that diabetes might be linked to damage to the pancreas