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Another B-vitamin, vitamin B 2 , riboflavin, as a photosensitizing compound 359 , gives rise to the oxidative cleavage of folic acid and 5-methyl-THF by visible light, which is absorbed by and yields excited states of riboflavin 356,360,361

These therapies target specific aspects of the immune-mediated disease process, focusing on reducing early disease activity that is hypothesized to contribute to long-term disability [11]