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However, both compounds individually cause: Nausea (60-80% of users at higher doses) Vomiting (20-35%) Diarrhea (25-40%) Injection site reactions (15-25%) Potential pancreatitis (rare but serious) Combining these compounds could theoretically amplify these effects, though the actual incidence and severity remain unstudied

They are not recommended for anyone under 18, or for people who are pregnant or breastfeeding

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Here are some examples: If you lose weight 0.5 lbs slower than your target each week, reduce caloric intake by 250 kcal daily (500*0.5)