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The phosphorylated polyubiquitin chains are recognized by mitochondrial autophagy receptors, such as BNIP3 (BCL2/Adenovirus E1B 19 kDa Interacting Protein 3) and p62, and mediate mitochondrial autophagy by binding to lipidated microtubule-associated protein light chain 3 II (LC3 II)

Hydration strategies Aggressive hydration is the first-line intervention for palpitations in people experiencing significant GI side effects on semaglutide

Acute administration of the GLP-1 Receptor agonist lixisenatide diminishes postprandial insulin secretion in healthy subjects but not in type 2 diabetes, associated with slowing of gastric emptying

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