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NGF binds to its high-affinity receptor TrkA, promoting axonal growth cone formation and epidermal neurite extension, thereby increasing intraepidermal nerve fiber density, enhancing peripheral sensitivity, and aggravating itch perception (101, 102)

According to FOX and ESPN's Kevin Seifert, Peterson "vomited upon arrival" in Detroit after swallowing his wad of chewing tobacco on what was described as a "bumpy" flight

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