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The researchers note that further studies are needed to determine the causality between the drug and the increased incidence of NAION

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(1) The normal control group was injected with 09 % saline daily

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Indeed, the insoluble complexes of bile salts can activate lumen-facing TGR5 receptors, while they cannot cross plasma membranes to activate intra-cellular GLP-1-suppressant FXR receptors

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