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Molly Natchipolsky, a spokesperson for the National Center for Complementary and Integrative Health, told me via email that the NCCIHs research team studying natural products is not aware of any supplement that can have similar effects or mechanisms to current GLP-1 agonists. One reason why GLP-1 agonist drugs work so well is because they increase the presence of the hormone in the body for a prolonged period of time

Interestingly, Iwamoto et al

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HK-Cu is widely used in regenerative medicine, functional medicine, longevity, sports recovery, and hair health protocols due to its ability to activate genes associated with cell repair and the production of structural proteins

Most common physical side effects typically diminish within 4 to 6 weeks