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The cell line was cultured in basal bronchial epithelial cell basal medium (BEBM) (Lonza, Walkersville, MD) supplemented with 2 ml of bovine pituitary extract and 0.5 ml of: insulin, hydrocortisone, retinoic acid, transferrin, triiodothyronine, epinephrine, and human recombinant epidermal growth factor (Lonza, Walkersville, MD)

(Marlboro had bought the rights to the music from United Artists.) The campaign, created by the Leo Burnett agency, turned Marlboro into the top-selling cigarette brand in the U.S., and later the world

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