Globally available over-the-counter 9 Included in: WHO policy recommendation and Model List of Essential Medicine since 2009 30-32 European Network for Smoking and Tobacco Prevention (ENSP) Tobacco Dependence Treatment Guidelines 33 NRT Combination Therapy is recommended by NICE as a first-line treatment option8 NRT single therapy is recommended by NICE as a second-line treatment option 8 Cytisine: Suitable for 18+18 Included in: World Health Organizations Policy Recommendation and Model List of Essential Medicines 2024 30.31 ENSP Tobacco Dependence Treatment Guidelines 33 Under consultation to add as first line treatment option 8 Varenicline: Suitable for 18+ 19 Included in: World Health Organizations Policy Recommendation and Model List of Essential Medicines 2021 30.31 ENSP Tobacco Dependence Treatment Guidelines 33 Varenicline is recommended by NICE as a first-line treatment option 8 Bupropion: Suitable for 18+20 Included in: World Health Organizations Policy Recommendation and Model List of Essential Medicines 2021 30.31 ENSP Tobacco Dependence Treatment Guidelines 33 Bupropion is recommended by NICE as a second-line treatment option 8 To keep in mind: NRT Combination Therapy is one of the most effective ways to help your patient quit for good 8 Speed of action and cravings relief Observational field studies indicate that cue-induced cravings are substantially responsible for relapse to smoking 35

The Burley, DFC and DAC varieties are purchased on an open market system
The mayors endorsing Dixon are Max Duncan (Aliso Viejo), John Gabbard (Dana Point), Don Caskey (Laguna Hills), Gene Johns (Laguna Niguel), Lauren Kleiman (Newport Beach), Rick Loeffler (San Clemente) and John Campbell (San Juan Capistrano)
Tobacco Jam 50 by Assaf is an extrait de parfum centered on tobacco, incense, and woods, conceived with a very high fragrance concentration
Still, many continue to smoke