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Starting from this nucleation complex, a fast cooperative growth towards the 5-tail occurs by serial addition of further disks and concomitant packaging of the 5'-segment of the RNA, which is drawn up through the central channel
The researchers undertook a randomised trial at various sites across Switzerland, involving 1,246 adults
Ammonia is pretty pungent and corrosive, so use gloves and make sure the area is well-ventilated
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