The findings revealed that L-theanine significantly reduced C-reactive protein (CRP) in the blood and lowered pro-inflammatory cytokines specifically in the hippocampus, effectively mitigating cognitive and memory decline in the animal models
This prebiotic promotes the growth of Akkermansia muciniphila, keystone gut bacteria essential for boosting GLP-1 signaling and enhancing gut barrier function
These models are available from the BioModels database (see Data Availability)
Six metabolites have been identified: 2-ethylisonicotinamide, carbonyl-dihydropyridine, thiocarbonyl-dihydropyridine, S-oxocarbamoyl dihydropyridine, 2-ethylthioisonicotinamide, and ethionamide sulfoxide, the latter having significant antimycobacterial activity (Henderson et al., 2008
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