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Effect of etamicastat on the renal expression of dopamine and endothelin B receptors In D 2 / mice, relative to D 2 +/+ littermates, the renal protein expressions of D 3 R and ETBR were increased

CKD prevalence is substantial among people with T2D (up to ~ 50%), and obesity is estimated to increase lifetime risk of CKD by 25% [5, 6]

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