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I had to repeat my question about a product three times before I finally got a half-hearted answer that left me more confused than informed

Fourth, cigarette smoke triggers the activation of pulmonary alveolar macrophages, leading to superoxide and hydrogen peroxide production and thereby contributing to the oxidative damage of DNA and RNA, increasing the likelihood of carcinogenesis 33

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A 2018 study in The New England Journal of Medicine estimated that reducing nicotine levels could lead to 5m fewer smokers in the first year and prevent over 8m tobacco-related deaths by 2100

On the contrary, they bring about cancer and other illnesses