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These studies demonstrate that the lower levels of harmful chemicals that are present in THS aerosol do indeed result in reduced exposure, as measured for the biomarkers reported in these studies

Charles Dana Gibson, Bayard Jones, William H

Studies in mice investigating the effects of e-cigarettes on different brain regions have found that e-cigarette exposure during pregnancy can alter the transcriptome of the frontal cortex (1316 mg/mL nicotine), increase global DNA methylation within the brain (1316 mg/mL nicotine), and dysregulate gene expression in the hippocampus (13 mg/mL nicotine) [176]

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