The goal is to find the minimum effective dose that provides the desired results with minimal side effects
Antihypertensive efficacy of hydrochlorothiazide as evaluated by ambulatory blood pressure monitoring: a meta-analysis of randomized trials
Its main missions are multiple and intimately linked: Energy metabolism: glucose management (storage as glycogen, release as needed), regulation of certain lipids, synthesis of plasma proteins Storage: vitamins (A, D, B12), minerals and energy reserves Transformation: metabolism of molecules from food, the environment, and medications Bile production: key role in lipid digestion and elimination of certain waste products Bile is produced by the liver and then released into the intestine, often via the gallbladder , which stores and concentrates it
Wirthgen E, Hoeflich A, Rebl A, Gnther J
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