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An acute toxicity study established that the LD 50 cut-off dose for the ethanolic extract of H

The satiety-inducing effects of GLP-1 RAs, combined with their ability to address hyperglycemia, make them a valuable tool for managing obesity and metabolic disorders

The same trends in cell viability, GLP-1R expression and autophagy suggested the potential connections in this pathological procedure of high glucose-induced toxicity in renal tubular epithelial cells

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As mechanistic insights into iron homeostasis, lipid peroxidation, and immunometabolic interactions continue to deepen, alongside progress in drug delivery, gene editing, and regenerative medicine, therapies targeting ferroptosis may represent a promising new paradigm in OA management, ultimately enhancing joint function and overall quality of life for affected individuals