According to prescribing information and the company's safety disclosures, you should not use GLP-1 medications - or should only do so under specialist supervision - if you have a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2, active or recent pancreatitis, severe gastrointestinal disorders that may be worsened by delayed gastric emptying, are pregnant, planning to become pregnant, or breastfeeding, or have severe kidney disease
Khoshdel A, Kheiri S, Nasiri J, et al
Additionally, they can talk to you about other alternatives to semaglutidetirzepatide, liraglutide, dulaglutide, lixisenatide, exenatide, which may be just as if not more suitable to helping you achieve your health goals, she says
BMJ Open 2020, 10: e033297
This regulation helps prevent both buildup of damaged proteins and excessive proteolytic (protein breakdown)