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Other neuroprotective mechanisms potentially involved in the treatment of cognitive disorders as well as cerebrovascular disease and epilepsy suggest that GLP-1RAs can enhance the viability of neurons and restore neurite outgrowth by stimulating neurotrophic factors, thus increasing subventricular zone progenitor cells, decreasing apoptosis and the level of pro-inflammatory factors, and strengthening the bloodbrain barrier 37

Safety, Quality, and Compliance Regulatory status: BPC-157 is not FDA-approved for therapeutic use in humans

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Curr Pharm Des 16:12241234 Sikiric P, Seiwerth S, Rucman R, Turkovic B, Rokotov DS, Brcic L, Sever M, Klicek R, Radic B, Drmic D et al (2014) Stable gastric pentadecapeptide BPC 157-NO-system relation

Additionally, mitochondria play a key role in calcium homeostasis, buffering cytosolic calcium in excitable cells