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In recent years, the role of GPX3 in oxidative stress has been reported, for example: GPX3 can inhibit the expression of HIF1- by regulating ROS, thereby inhibiting the growth of melanoma cells (Yi et al., 2019)

There are correlations between PyroGlu, Glu, and GPX1 activity and some biochemical, respiratory, and severity markers

The prevalence of this polymorphism in human populations averages 3040%, but it varies from 0% to over 40%, depending on geographic location, with minimal difference between genders [2]

Lin LF, Doherty DH, Lile JD, Bektesh S, Collins F