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Aschner P, Kipnes MS, Lunceford JK, et al

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Clinicians should monitor patients for potential adverse effects including pancreatitis (severe, persistent abdominal pain), gallbladder disease (right upper quadrant pain), diabetic retinopathy complications (especially with rapid glucose improvement), acute kidney injury with dehydration, and hypoglycemia when combined with insulin or sulfonylureas

[3] However, clinical experience suggests that patients may benefit from a gradual approach to reaching fiber targets, particularly when initiating GLP-1 therapy or during dose escalation periods

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