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demonstrated that tumors produce ammonia through glutamine metabolism, which is converted into glutamate and downstream amino acids via reductive amination to support cellular nitrogen requirements

A compound initially developed as an antifungal agent

doi: 10.1016/j.ejca.2005.04.028 [DOI] [PubMed] [Google Scholar] 37.Hershman DL, Unger JM, Crew KD, et al