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Korean dermatology has been working with regenerative actives for decades, and ingredients like PDRN (polydeoxyribonucleotide, derived from salmon DNA) offer similar repair and anti-ageing benefits through gentler biological pathways

Activation of YAP can induce the expression of SLC7A11, thereby enhancing cystine uptake by System XC-, increasing GSH level, thereby increasing GPX4 synthesis, thus reducing ROS level and inhibiting ferroptosis [16, 17]

All constructs were prepared using homologous recombination (CloneExpress One Step Cloning Kit, Vazyme)

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