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Collectively, these results reveal that agents including DFX, statins, tirilazad, clazosentan, and magnesium sulfate have yet to demonstrate consistent long-term efficacy

Indeed, polymorphisms in acid mammalian chitinase are associated with asthma, further supporting the involvement of acid mammalian chitinase in asthma development 65

In experiments to determine suppression of cell toxicity resulting from ESA or ML162 by silencing expression of individual ACSL genes, doses of ESA or ML162 were selected such that there was 515% remaining viability in cells transfected with non-targeting siRNA following 24 h of treatment

Doses are usually lower for people with kidney problems

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